When working in an IVF lab there are different ways to assess embryos. You can score embryos using morphology and traditional grading, you can use preimplantation genetic testing (PGT) to get the genetic profiling of embryos prior to implantation, and finally you can analyse morphokinetic parameters of embryo development using time-lapse information. How do we bring together morphology, PGT and time-lapse to improve our embryo selection?
I joined Vitrolife at the beginning of this year and was very flattered to have been asked to write not only the first blog of the year, but also the first blog from Vitrolife’s Genomics Business Unit – an application area close to my heart.
Living in Cambridge, UK where the structure of DNA was first discovered and where the technique of IVF was pioneered I feel very lucky to be part of this field where we are learning more and more about the role that genetics plays in infertility. Watson and Crick famously discussed their results in the Eagle pub, still popular with Cambridge students today and IVF pioneer Robert Edwards worked in the physiology lab just a few streets away.
Our guest blogger Dr. Gary Harton is well known in the reproductive genetics field, where he has spent his entire career. In this blog post he will take you through the basics, the history, the advantages, the debates and what is yet to be determined when it comes to preimplantation genetic testing in assisted reproduction.
When working with assisted reproduction we use a lot of different terms and definitions. This blog post will give you an update on the rather new acronym PGT (preimplantation genetic testing) as well as a glossary of common and useful terms.
EmbryoScope time-lapse system is used in combination with preimplantation genetic testing at IVF Riga. Medical Director Dr. Violeta Fodina says that this makes it possible to select only the best embryos for genetic testing, thereby reducing the time to pregnancy and delivery of a child. Watch her story here.
Lab Director and co-owner Dr. Oliver Sterthaus at Fertisuisse in Switzerland built a completely new IVF clinic in 2014 with his colleagues. When setting up the new lab, convenience and workflow were important factors, and therefore they decided to use the dynamic Octax NaviLase laser system for all laser procedures. Watch his story here.
Many clinics have seen the benefit of making time-lapse a standard of care for their patients. The same is true for Preimplantation Genetic Screening (PGS). The fact that there are two such widely implemented techniques has created some questions about which new technology will offer the best treatment options for improving clinical outcome. In this webinar Dr. Tine Qvistgaard Kajhøj shows how time-lapse and PGS can be used together to offer the best overall possibility for improving outcomes and clinical workflow.
Almost three decades ago, preimplantation genetic testing (PGT) was applied clinically for the first time by pioneers like Alan Handyside in the UK and Yuri Verlinsky in the US. Still, introducing this procedure can be a challenge. In this blog post you will get a practical guidance of what to consider when introducing PGT in your IVF clinic.