The concept of fast freezing or vitrification was first described more than 80 years ago by Basile J. Luyet, the so-called Father of Cryobiology (Luyet, 1937). He showed that supercooled solutions could be solidified without crystallization, forming a glass-like state. Already then, the potential of the technique and the associated challenges were in the research spotlight. Today, we’ve managed to overcome all methodological-related issues of vitrification. It has evolved into a reliable and efficient method to freeze oocytes and embryos. Vitrification is used for medically assisted reproduction and fertility preservation: the goal is to ensure the maximum survival rate with the highest level of biosafety. In this blog post, we will compare closed and open carrier devices for vitrification.
The simple answer is, it can’t. In a well-functioning culture system, the oil should only act as a cover, protecting the gametes and embryos from changes in the environment and potential contaminants. But if the oil quality is sub-optimal, it can decrease embryo development. Most oils are produced from petroleum, which means that embryotoxic components may be present due to the production process and origin of the raw materials.
Why there is a need for the sustainable development goals
The establishment in 2015 of the Sustainable Development Goals (SDGs) has created a global consensus on the development framework for a better world. However, as we look to the next decade, there is significant cause for concern about the future. The IPCC’s Sixth Assessment report, released in August 2021, confirms that it is indisputable that human influence has warmed the climate system, raising global surface temperature. The report confirms that there is no going back from some changes that are already affecting the climate system. These changes in the climate are widespread, rapid and intensifying and impacts are affecting every region on Earth, including the oceans.
Introduction to Medical Device Regulations - MDR
For 30 years medical devices have been governed by the Medical Device Directive (MDD) implemented in EU/EEA in 1993, and there have been quite a few developments in the field of medical devices since then. For instance, apps used as stand-alone products for different medical purposes have become a reality. The general population has become older, patients are more used to finding medical information on the internet, and the beauty industry uses more advanced and invasive techniques than before. These changes, and more, have prompted an update of the control of medical devices for some time. Eventually, the new Medical Device Regulations (MDR) were developed and came into force on May 26, 2021. From this date, all new medical devices and the manufacturer’s quality management system must comply with the MDR. Implementation deadlines for existing devices are dependent on classification and expiry of existing MDD certificates.
This year, online was the place to be when participating in the 76th annual meeting of ASRM. In this blog post, thoughts and reflections from the Vitrolife team have been collected on some of the scientific content presented at the meeting.
The 36th annual meeting of ESHRE took place online this year, with more than 12,000 registered participants. Like last year, the Vitrolife team has put together our thoughts and reflections on some of the scientific content from the meeting. We also offer the opportunity to watch our recorded scientific symposium again.
It is with great sadness that Vitrolife posts this memoriam for Prof Michelle Lane, who passed away last week.
What do you as an IVF professional look for when setting up an entirely new clinic and laboratory? For the laboratory manager, Helle Bendtsen at Aleris-Hamlet Fertility in Copenhagen, the advantage of having one supplier for all of their procedures in the laboratory was clear quite quickly: ‘When setting up the clinic we received great support from Vitrolife in terms of selecting all the products for the entire IVF procedure. From oocyte retrieval all the way to vitrification and transfer’, she says and adds: ‘Previously I’ve worked with products from several different suppliers, but now I can truly see the benefits with having all our products from Vitrolife.’
“A picture is worth a thousand words” – this old proverb is embraced and applied by medical device manufacturers all around the world, but why is that?
The answer to that question starts with the fact that most countries’ health authorities require medical device manufacturers to provide product information to the users in their local language. This is a not a problem for manufacturers who produce and distribute big volume products where an entire batch will be sold in only one country. They simply produce batches dedicated to the specific country with product information in that local language.
This year Philadelphia hosted the annual American Society for Reproductive Medicine meeting for thousands of delegates from all over the world. Similar to previous years, IVF professionals gathered to present or listen to the latest scientific developments in the field of assisted reproduction. We have collected some of our thoughts and reflections of the scientific content of the meeting in this blog post.