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Together. All the way.

Together. All the way. – A blog about creating optimal conditions for successful IVF

Together. All the way. – A blog about creating optimal conditions for successful IVF
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The road to successful ICSI

By Hubert Joris, Sep 24, 2019

Different assisted fertilisation methods were developed and implemented in the field of IVF during 1980-1990. Out of these methods, intracytoplasmic sperm injection (ICSI) is the most successful method developed1 and is considered to be one of the major breakthroughs in this field since the birth of Louise Brown in 1978. While assisted fertilisation techniques, including ICSI, were introduced to overcome fertilisation failure in cases of severe male infertility, ICSI is today used in > 60 % of all IVF cycles globally.2

ICSI has frequently been described as 'an accident' in the lab. For me, being part of the development of the ICSI technique, I would rather describe ICSI as an inevitable consequence of the procedure used to perform subzonal insemination. The aim of this blog is, however, not to cover the history of ICSI but rather to focus on aspects that support successful ICSI in the IVF laboratory. 

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Do you know the different laser applications? Here are 4 ways to use your laser in the IVF lab

By Dr. Victoria Sanchez, Aug 19, 2019

Having a laser system can help address a variety of cases in ART while optimising the workflow. It is, therefore, common today for embryology laboratories to have a laser system attached to the microscope at the ICSI workplace.

You are probably already familiar with the use of lasers for assisted hatching or embryo biopsy, since these are the most widely spread applications. There are, however, other ways in which you and your patients can benefit from the use of a laser system in the lab.

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Thoughts and reflections from ESHRE 2019

By Vitrolife, Jul 9, 2019

Once again, the biggest event in the field of assisted reproduction, ESHRE, has taken place. No less than 12.003 participants gathered in warm Vienna for updates on the latest science within the field of IVF and of course to meet with old and new friends. As usual the Vitrolife team has put together our thoughts and reflections on some of the scientific content at the meeting. We also provide a new chance to watch our symposium.

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Optimising transfer outcome with the use of EmbryoGlue [webinar recording]

By Vitrolife, Jul 4, 2019

It has been 20 years since Prof. Gardner’s team first published on the effects of hyaluronan (also known as hyaluronic acid) on preimplantation embryo culture and transfer, and so this is a poignant time to reflect on the role of this remarkable macromolecule in assisted reproduction.

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20 years on – Reflections on Hyaluronan

By Prof. David K Gardner, Jun 3, 2019

It has been 20 years since my team first published on the effects of hyaluronan (also known as hyaluronic acid) on preimplantation embryo culture and transfer1, and so this is a poignant time to reflect on the role of this remarkable macromolecule in assisted reproduction.

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EmbryoScope use – a sneaky glimpse at the UK

By Dr. Stephen Troup, Consultant Reproductive Scientist, May 15, 2019

No one can argue against the value of high-quality, correctly designed, appropriately powered, multicentre prospective RCTs (or even better systematic reviews of a number of such studies) as the ideal mechanism to generate evidenced-based medicine. But I’m afraid the assisted conception world is far from ideal in this respect and high-quality studies are notoriously difficult to carry out. Unfortunately, some might consider this the situation with evidence in support of the EmbryoScope and morphokinetic embryo selection algorithms, although I’m not sure I’d entirely agree. 

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Thoughts and reflections from PGDIS 2019

By Prof. Alan H Handyside, MA PhD, Scientific Advisor, Apr 30, 2019

Introducing Vitrolife genomics at PGDIS 2019

The International Society for Preimplantation Genetic Diagnosis (PGDIS) was formed in the early 1990s by a group of clinicians and scientists attending the inaugural meeting in Chicago, based in the historic Drake Hotel, and organised by the late Yury Verlinksy and colleagues, who was one of the pioneers of preimplantation genetic diagnosis, recently renamed preimplantation genetic testing (PGT). Last year, I became President of the Society and have been very involved in organising the 18th, now annual, meeting in Geneva, Switzerland. The meeting attracted about 350 attendees from 45 countries including nearly 40 from Russia.

This was an important first opportunity for the newly formed Vitrolife genomics team (who turned up in force!) to meet many of our customers for SNP genotyping and karyomapping for diagnosis of monogenic disease (PGT-M) and next generation sequencing (NGS) based chromosome copy number analysis for detection of aneuploidy (PGT-A). 

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Why local anesthesia during oocyte retrieval is beneficial for the patient and clinic [customer story]

By Vitrolife, Mar 27, 2019

Local anesthesia combined with conscious sedation is the preferred method for oocyte retrieval at the IVF clinic Fertilitetscentrum in Sweden. Dr. Matts Wikland, MD, PhD, Associate Professor explains why.

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How traditional grading, PGT and time-lapse complement each other

By Dr. Cristina Hickman, Feb 26, 2019

When working in an IVF lab there are different ways to assess embryos. You can score embryos using morphology and traditional grading, you can use preimplantation genetic testing (PGT) to get the genetic profiling of embryos prior to implantation, and finally you can analyse morphokinetic parameters of embryo development using time-lapse information. How do we bring together morphology, PGT and time-lapse to improve our embryo selection?  

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The genomics revolution in IVF is here to stay

By Dr. Sally Cartwright, Jan 31, 2019

I joined Vitrolife at the beginning of this year and was very flattered to have been asked to write not only the first blog of the year, but also the first blog from Vitrolife’s Genomics Business Unit – an application area close to my heart.

Living in Cambridge, UK where the structure of DNA was first discovered and where the technique of IVF was pioneered I feel very lucky to be part of this field where we are learning more and more about the role that genetics plays in infertility. Watson and Crick famously discussed their results in the Eagle pub, still popular with Cambridge students today and IVF pioneer Robert Edwards worked in the physiology lab just a few streets away.

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